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GMC Sierra 2500 HD Air Filter & Cleaner

Your Sierra 2500 HD is a prized possession.

The vehicle in your driveway is head and shoulders above the rest compared to all the other cars, trucks, and SUVs these days. While it's not hard to find replacement parts for GMC vehicles, these days only the highest quality are required to repair your car or truck. Obviously, you didn't buy your Sierra 2500 HD unless you knew that you wanted performance and rugged design both rolled up into one car, truck, or SUV. You picked your Sierra 2500 HD because its reliability and trusted quality struck a chord inside you; so why would you settle for anything but the best when it comes to great quality auto parts?

Why Air Filter & Cleaner replacement is so important.

An important factor in fuel efficiency is the appropriate mix of air and fuel. Your GMC Sierra 2500 HD uses a paper or cloth air filter to remove dust and debris from the air stream before it enters the intake manifold, mixes with your fuel, and gets detonated. Without an air filter or air cleaner in your engine, your fuel would be filled with particulates from outside. This will plug up your injectors and rob your engine of fuel; making it difficult for your engine to generate power. And unless your GMC Sierra 2500 HD air filter is replaced regularly your engine will be robbed of the necessary air flow needed to maintain optimum fuel efficiency. Clearly, replacement air filters are a necessity for everyone.

You've tried the rest, now try the best.

Select Your YearGet your Sierra 2500 HD back on the road with the highest quality new or rebuilt parts from the experts at Car Parts Discount. When your GMC requires a new replacement Air Filter & Cleaner, there's no need to go somewhere besides the authority, Car Parts Discount. Don't let a broken Air Filter & Cleaner bring about the demise of your car, truck, or SUV, and don't risk lowering its resale value by installing anything but the highest quality replacement parts. All the GMC Sierra 2500 HD Air Filter & Cleaner parts on this page will fit vehicles made in 2017, 2016, 2015, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007, 2006, 2005, 2004, 2003, 2002, 2001. Choose your year below to refine your search.

Info: Select your make and model in the red title bar above so we can show the parts you need.
GMC Sierra 2500 HD Air Filter, OEM: 5499WSBosch
2001-2017 GMC Sierra 2500 HD Bosch Air Filter 5499WS
4.55, Save 40%   NEW ITEM
OEM: 5499WS, Item: 1409805
  In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: PA5314Premium Guard
2001-2016 GMC Sierra 2500 HD Premium Guard Air Filter PA5314
5.45, Save 40%   NEW ITEM
OEM: PA5314, Item: 1291511
  In Stock, Usually ships within 1 business day
Select year, make, model above to verify this part fits your vehicle

Auto Extra
2004-2014 GMC Sierra 2500 HD Auto Extra Air Filter 619-42487
6.35, Save 40%   NEW ITEM
OEM: 619-42487, Item: 389206
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: PA5315Premium Guard
2001-2017 GMC Sierra 2500 HD Premium Guard Air Filter PA5315
7.35, Save 39%   NEW ITEM
OEM: PA5315, Item: 1291512
  In Stock, Usually ships within 1 business day
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Auto Extra
2004-2005 GMC Sierra 2500 HD Auto Extra Air Filter 619-46678
8.85, Save 40%   NEW ITEM
OEM: 619-46678, Item: 389345
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: PA6146Premium Guard
2011-2016 GMC Sierra 2500 HD Premium Guard Air Filter PA6146
9.15, Save 40%   NEW ITEM
OEM: PA6146, Item: 1291735
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: 143-3435/1433435Denso
2001-2015 GMC Sierra 2500 HD Denso Air Filter 143-3435
10.35, Save 40%   NEW ITEM
OEM: 143-3435, Item: 585842
  Only 6 left In Stock, Usually ships within 1-2 business days
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GMC Sierra 2500 HD Air Filter, OEM: LX2562Mahle
2001-2014 GMC Sierra 2500 HD Mahle Air Filter LX2562
10.75, Save 40%   NEW ITEM
OEM: LX2562, Item: 1175458
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: AF1052Hastings
2001-2017 GMC Sierra 2500 HD Hastings Air Filter AF1052
13.75, Save 39%   NEW ITEM
OEM: AF1052, Item: 398776
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: CA8755AFram
2001-2017 GMC Sierra 2500 HD Fram Air Filter CA8755A
14.95, Save 39%   NEW ITEM
OEM: CA8755A, Item: 94356
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: CA8756Fram
2001-2017 GMC Sierra 2500 HD Fram Air Filter CA8756
14.95, Save 39%   NEW ITEM
OEM: CA8756, Item: 94354
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: AF1119Hastings
2001-2005 GMC Sierra 2500 HD Hastings Air Filter AF1119
15.75, Save 39%   NEW ITEM
OEM: AF1119, Item: 398805
  Only 3 left In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: AF513Hastings
2002 GMC Sierra 2500 HD Hastings Air Filter AF513
16.05, Save 39%   NEW ITEM
OEM: AF513, Item: 399028
  Only 3 left In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: 46678WIX
2004-2005 GMC Sierra 2500 HD WIX Air Filter 46678
17.35, Save 39%   NEW ITEM
OEM: 46678, Item: 663417
  In Stock, Usually ships within 1-2 business days
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GMC Sierra 2500 HD Air Filter, OEM: TGA8755AFram
2001-2017 GMC Sierra 2500 HD Fram Air Filter TGA8755A
18.35, Save 40%   NEW ITEM
OEM: TGA8755A, Item: 417567
  Only 4 left In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: A3085CFACDelco
2001-2013 GMC Sierra 2500 HD ACDelco Air Filter A3085CF
19.95, Save 39%   NEW ITEM
OEM: A3085CF, Item: 691619
  Only 7 left In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: A1618CACDelco
2001-2005 GMC Sierra 2500 HD ACDelco Air Filter A1618C
20.35, Save 39%   NEW ITEM
OEM: A1618C, Item: 691581
  In Stock, Usually ships within 1 business day
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ACDelco
2014-2016 GMC Sierra 2500 HD ACDelco Air Filter A3181CF
21.05, Save 39%   NEW ITEM
OEM: A3181CF, Item: 899178
  Only 4 left In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: AF1530Hastings
2011-2016 GMC Sierra 2500 HD Hastings Air Filter AF1530
21.15, Save 39%   NEW ITEM
OEM: AF1530, Item: 410946
  Only 3 left In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: A3181CACDelco
2001-2016 GMC Sierra 2500 HD ACDelco Air Filter A3181C
18.13, Save 49%   NEW ITEMPOPULAR
OEM: A3181C, Item: 691648
  In Stock, Usually ships within 1 business day
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ACDelco
2017 GMC Sierra 2500 HD ACDelco Air Filter A3231C
25.45, Save 39%   NEW ITEM
OEM: A3231C, Item: 1419155
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: 49314WIX
2016 GMC Sierra 2500 HD WIX Air Filter 49314
25.55, Save 39%   NEW ITEM
OEM: 49314, Item: 663470
  In Stock, Usually ships within 1-2 business days
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GMC Sierra 2500 HD Air Filter, OEM: CA11033Fram
2011-2016 GMC Sierra 2500 HD Fram Air Filter CA11033
26.05, Save 39%   NEW ITEM
OEM: CA11033, Item: 95048
  Only 5 left In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: A3141CACDelco
2011-2016 GMC Sierra 2500 HD ACDelco Air Filter A3141C
26.15, Save 39%   NEW ITEM
OEM: A3141C, Item: 691634
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: PA5638Premium Guard
2006-2010 GMC Sierra 2500 HD Premium Guard Air Filter PA5638
31.65, Save 39%   NEW ITEM
OEM: PA5638, Item: 1313720
  In Stock, Usually ships within 1 business day
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AEM
2001-2017 GMC Sierra 2500 HD AEM Air Filter 28-20129
Add for Price, Save 25%   NEW ITEM
OEM: 28-20129, Item: 1449025
  Only 5 left In Stock, Usually ships within 1-2 business days
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GMC Sierra 2500 HD Air Filter, OEM: AF2400Hastings
2006-2010 GMC Sierra 2500 HD Hastings Air Filter AF2400
40.35, Save 39%   NEW ITEM
OEM: AF2400, Item: 1023749
  In Stock, Usually ships within 1 business day
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GMC Sierra 2500 HD Air Filter, OEM: RF-1042/RF1042K&N
2007-2008 GMC Sierra 2500 HD K&N Air Filter RF-1042
Add for Price, Save 26%   NEW ITEM
OEM: RF-1042, Item: 859864
  In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: A3087CACDelco
2006-2010 GMC Sierra 2500 HD ACDelco Air Filter A3087C
45.25, Save 39%   NEW ITEM
OEM: A3087C, Item: 691620
  In Stock, Usually ships within 1 business day
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: RF-1041/RF1041K&N
2001-2006, 2014-2017 GMC Sierra 2500 HD K&N Air Filter RF-1041
Add for Price, Save 26%   NEW ITEM
OEM: RF-1041, Item: 860141
  In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: 33-2135/332135K&N
2001-2017 GMC Sierra 2500 HD K&N Air Filter 33-2135
Add for Price, Save 25%   NEW ITEM
OEM: 33-2135, Item: 859569
  Only 9 left In Stock, Usually ships within 1-2 business days
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aFE Power
2001-2014 GMC Sierra 2500 HD aFE Power Air Filter 31-10004
Add for Price, Save 28%   NEW ITEM
OEM: 31-10004, Item: 1443006
  Only 4 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: RC-5046/RC5046K&N
2001-2006 GMC Sierra 2500 HD K&N Air Filter RC-5046
Add for Price, Save 26%  
OEM: RC-5046, Item: 860056
  Only 5 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: RU-5177HBK/RU5177HBKK&N
2007-2010 GMC Sierra 2500 HD K&N Air Filter RU-5177HBK
Add for Price, Save 30%   NEW ITEM
OEM: RU-5177HBK, Item: 861850
  In Stock, Usually ships within 1-2 business days
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GMC Sierra 2500 HD Air Filter, OEM: RC-4900/RC4900K&N
2001-2005 GMC Sierra 2500 HD K&N Air Filter RC-4900
Add for Price, Save 26%   NEW ITEM
OEM: RC-4900, Item: 862070
  Only 4 left In Stock, Usually ships within 1-2 business days
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aFE Power
2001-2014 GMC Sierra 2500 HD aFE Power Air Filter 30-10004
Add for Price, Save 35%   NEW ITEM
OEM: 30-10004, Item: 1441325
  In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

aFE Power
2006-2010 GMC Sierra 2500 HD aFE Power Air Filter 11-10101
Add for Price, Save 28%   NEW ITEM
OEM: 11-10101, Item: 1443020
  Only 3 left In Stock, Usually ships within 1-2 business days
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aFE Power
2011-2015 GMC Sierra 2500 HD aFE Power Air Filter 31-80209
Add for Price, Save 28%   NEW ITEM
OEM: 31-80209, Item: 1441459
  Only 1 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: CA10161Fram
2006-2010 GMC Sierra 2500 HD Fram Air Filter CA10161
67.15, Save 39%   NEW ITEM
OEM: CA10161, Item: 95296
  Only 6 left In Stock, Usually ships within 1 business day
Select year, make, model above to verify this part fits your vehicle

aFE Power
2011-2015 GMC Sierra 2500 HD aFE Power Air Filter 30-10209
Add for Price, Save 34%   NEW ITEM
OEM: 30-10209, Item: 1442043
  In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

aFE Power
2012 GMC Sierra 2500 HD aFE Power Air Filter 31-10209
Add for Price, Save 34%   NEW ITEM
OEM: 31-10209, Item: 1442042
  In Stock, Usually ships within 1-2 business days
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GMC Sierra 2500 HD Air Filter, OEM: RC-5112/RC5112K&N
2001-2005 GMC Sierra 2500 HD K&N Air Filter RC-5112
Add for Price, Save 29%   NEW ITEM
OEM: RC-5112, Item: 862781
  Only 2 left In Stock, Usually ships within 1-2 business days
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GMC Sierra 2500 HD Air Filter, OEM: RF1041K&N
2001-2006, 2014-2017 GMC Sierra 2500 HD K&N Air Filter RF1041
73.05, Save 39%   NEW ITEM
OEM: RF1041, Item: 1457209
  Only 2 left In Stock, Usually ships within 1 business day
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: 33-2466/332466K&N
2011-2016 GMC Sierra 2500 HD K&N Air Filter 33-2466
Add for Price, Save 25%   NEW ITEM
OEM: 33-2466, Item: 861019
  Only 8 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: RC-5179/RC5179K&N
2005-2017 GMC Sierra 2500 HD K&N Air Filter RC-5179
Add for Price, Save 29%   NEW ITEM
OEM: RC-5179, Item: 861482
  In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

K&N
2005-2012 GMC Sierra 2500 HD K&N Air Filter RC-5177
Add for Price, Save 29%   NEW ITEM
OEM: RC-5177, Item: 862365
  In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: E-0781/E0781K&N
2005-2010 GMC Sierra 2500 HD K&N Air Filter E-0781
Add for Price, Save 25%   NEW ITEM
OEM: E-0781, Item: 860087
  Only 2 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

aFE Power
2001-2005 GMC Sierra 2500 HD aFE Power Air Filter 30-80062
Add for Price, Save 33%   NEW ITEM
OEM: 30-80062, Item: 1441369
  Only 4 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

Banks Power
2005-2014 GMC Sierra 2500 HD Banks Power Air Filter 42138
Add for Price, Save 33%   NEW ITEM
OEM: 42138, Item: 1348047
  Only 1 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

Banks Power
2005-2014 GMC Sierra 2500 HD Banks Power Air Filter 42138-D
Add for Price, Save 33%   NEW ITEM
OEM: 42138-D, Item: 1348048
  Only 2 left In Stock, Usually ships within 1-2 business days
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K&N
2017 GMC Sierra 2500 HD K&N Air Filter 33-5065
Add for Price, Save 36%   NEW ITEM
OEM: 33-5065, Item: 1422011
  Only 1 left In Stock, Usually ships within 1-2 business days
Select year, make, model above to verify this part fits your vehicle

GMC Sierra 2500 HD Air Filter, OEM: 143-3436/1433436Denso
2001-2006 GMC Sierra 2500 HD Denso Air Filter 143-3436
11.05, Save 39%   NO STOCK
OEM: 143-3436, Item: 585843
  Restock date not known
Select year, make, model above to verify this part fits your vehicle

aFE Power
2012 GMC Sierra 2500 HD aFE Power Air Filter 30-80209
Add for Price, Save 28%   NO STOCK
OEM: 30-80209, Item: 1459086
  Restock date not known
Select year, make, model above to verify this part fits your vehicle

aFE Power
2002-2003, 2005 GMC Sierra 2500 HD aFE Power Air Filter 31-80062
Add for Price, Save 28%   NO STOCK
OEM: 31-80062, Item: 1441454
  Restock date not known
Select year, make, model above to verify this part fits your vehicle